iba-1
- 50 μL
Product Information
| Description | Iba1 rabbit polyclonal |
| Protein full name | Allograft inflammatory factor 1 |
| Synonyms | AIF1, G1, IBA1, IRT1, AIF-1, IRT-1 |
| Immunogen | Synthetic peptide within Human Iba1 aa 1-100 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 17kDa |
| Observed MW. | 17 kDa |
| Uniprot ID | P55008 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB |
Human, Mouse, Rat | 1: 1000 | THP-1, MOLT-4, U937, spleen, testis, hippocampus, brain |
Background
AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. (20944424). AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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