ABCG2
- 50 μL
Product Information
| Description | ABCG2 rabbit polyclonal |
| Protein full name | ABCG2 |
| Synonyms | ABC15, ABCG 2, ABCG2_HUMAN, ABCP, ATP binding cassette sub family G (WHITE) member 2, ATP binding cassette transporter G2, ATP-binding cassette sub-family G member 2, BCRP1, BMDP, Breast cancer resistance protein, CD338, CDw338, CDw338 antigen |
| Immunogen | KLH conjugated synthetic peptide derived from human ABCG2:571-655/655 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 72 kDa |
| Observed MW. | 72 kDa |
| Uniprot ID | Q9UNQ0 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | placenta |
Background
ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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