klotho
￥0
货号：YB13589
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | Klotho rabbit polyclonal |
| Protein full name | Klotho |
| Synonyms | KL antibody, Klotho peptide |
| Immunogen | KLH conjugated synthetic peptide derived from human Klotho:401-500/1012 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 113 kDa |
| Observed MW. | 113 kDa |
| Uniprot ID | Q9UEF7 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000 | kidney, fetal kidney, testis, fetal thymus |
Background
KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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