Anti-VEGF antibody
- 50 μL
Product Information
| Description | VEGF Rabbit monoclonal |
| Protein full name | Vascular endothelial growth factor A |
| Synonyms | VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse VEGFA |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Membrane |
| Uniprot ID | P15692, Q00731 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse | 1:100 | kidney |
Background
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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