TGFβ1
- 50 μL
Product Information
| Description | Anti-TGFB1(TGFβ1) Antibody |
| Protein full name | Transforming growth factor beta-1 proprotein |
| Synonyms | CED, DPD1, LAP, TGF beta 1, tgf beta1, TGFB, TGFB1, TGFbeta, tgfbeta1, tgf-beta1, TGFβ, TGFβ1, TGF-β1 |
| Immunogen | A synthetic peptide |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Glycosylated |
| Uniprot ID | P01137, P04202, P17246 |
Applications
| Applications | Species | Dilution | Positive Tissue | |||
| IHC | Human, Rat, Mouse | 1: 50-1: 200 | intestine, retina | |||
Background
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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