产品信息

蛋白质全称	犬尿氨酸-酮戊二酸转氨酶1
别名	Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Kyat1, Ccbl1, KATI, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase 1, Kat, HAT1, Kynurenine--oxoglutarate transaminase I
Uniprot ID	Q8BTY1
免疫原	小鼠HAT1重组蛋白
抗体亚型	IgG
预测分子量./观测分子量.	48 kDa / 48 kDa
纯化方式	亲和纯化

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应用

应用	物种	稀释	阳性样品
WB 免疫印迹	小鼠, 大鼠	1: 500-1: 1000	肝, 肾

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背景

This gene encodes a cytosolic enzyme and this protein catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia.

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图像

WB检测KAT1/HAT1蛋白(货号 GB111029). 样品: 经RIPA裂解液(货号G2002)处理的蛋白质. 封闭: 封闭: 3%脱脂牛奶(货号GC310001)溶于TBST溶液, 室温孵育1小时. —抗: 1: 500稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号GB23303), 1: 5000稀释, 室温孵育1小时.

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储存

储存条件	在-20℃下储存一年, 避免反复冻融.
储存缓冲液	含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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注意:

1.本产品仅供研究使用.

2.建议用一抗稀释液(G2025)稀释本产品.