CX43
- 100ul
Product Information
Description | Connexin 43 rabbit polyclonal |
Protein full name | Gap junction alpha-1 protein |
Synonyms | GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43 |
Isotype | IgG |
Predicted MW. | 43 kDa |
Observed MW. | 43 kDa |
Purity | Affinity purification |
Subcellular location | Cell junction, Endoplasmic reticulum |
Uniprot ID | P17302, P23242, P08050 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 1000-1: 5000 | HeLa, HepG2, SW480 |
IHC | Mouse, Rat | 1: 100-1: 500 | heart |
IF | Mouse, Rat | 1: 100-1: 500 | heart |
Background
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles .
Images
| Western blot analysis of GJA1 (GB11234) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using GJA1 (GB11234) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using GJA1 (GB11234) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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