Caspase9
- 100ul
Product Information
Description | Caspase-9 rabbit polyclonal |
Protein full name | Caspase-9 |
Synonyms | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9 |
Immunogen | Recombinant protein corresponding to Mouse Caspase9 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 50 kDa |
Observed MW. | 35/46 kDa |
Subcellular location | Cytoplasm, Nucleus |
Uniprot ID | Q8C3Q9 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse, Rat | 1: 800-1: 1000 | heart, brain, skeletal muscle |
Background
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increased in the response of cells to genotoxic stress and ABL1/c-Abl activation (By similarity).
Images
| Western blot analysis of Caspase-9 (GB11053-1) at dilution of 1: 1000 Lane 1: Mouse heart tissue lysate Lane 2: Mouse skeletal muscle tissue lysate Lane 3: Mouse brain tissue lysate Lane 4: Rat heart tissue lysate Lane 5: Rat skeletal muscle tissue lysate Lane 6: Rat brain tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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