Anti-p53 Rabbit pAb
- 50 μL
Product Information
Description | p53 rabbit polyclonal |
Protein full name | Cellular tumor antigen p53 |
Synonyms | Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53, P53 |
Immunogen | A synthesized peptide derived from human p53,corresponding to a region within N-terminal amino acids. |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytoplasm, Nucleus |
Predicted MW. | 44 kDa |
Observed MW. | 53 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 2000 | MCF7 |
IHC | Human, Mouse, Rat | 1: 50-1: 200 | brain |
IF/ICC | Human, Mouse, Rat | 1: 100-1: 500 | |
ELISA | Human, Mouse, Rat | 1: 20000-1: 40000 |
Background
TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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