Anti-Fas Ligand Rabbit pAb
- 50 μL
Product Information
Description | Fas Ligand rabbit polyclonal |
Protein full name | Tumor necrosis factor ligand superfamily member 6 |
Synonyms | Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, APT1LG1, CD95L, FASL, TNFSF6, FASLG, SPA |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1). |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cell membrane,Cytoplasmic vesicle lumen,Lysosome lumen,Nucleus,Secreted,Single-pass type II membrane protein |
Predicted MW. | 46 kDa |
Observed MW. | 14/31 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 2000 | heart |
Background
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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