pten
- 50 μL
Product Information
Description | PTEN rabbit polyclonal |
Protein full name | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
Synonyms | PTEN, MMAC1, TEP1, BZS, DEC, CWS1, GLM2, MHAM, PTEN1, 10q23del, PTENbeta |
Immunogen | A synthesized peptide derived from human PTEN, corresponding to a region within C-terminal amino acids. |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted, Cytoplasm, Nucleus |
Predicted MW. | 47 kDa |
Observed MW. | 54 kDa |
Uniprot ID | B2R904, F2YHV0, P60484, Q6ICT7 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat, Monkey | 1: 500-1: 2000 | Expressed in all adult tissues, including heart, brain, placenta, lung, liver, muscle, kidney and pancreas |
Background
PTEN(Phosphatase and tensin homolog) is also named as MMAC1, TEP1 and it modulates cell cycle progression and cell survival (blockage) through down-regulating the positive cell cycle-regulator (cycle D1) by its phosphatase activity and up-regulating the negative cell cycle regulator p21 (by its lipid phosphatase activity).
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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