rock2
- 50 μL
Product Information
Description | ROCK2 rabbit polyclonal |
Protein full name | ROCK2 |
Synonyms | p164 ROCK 2, p164 ROCK-2, Rho associated coiled coil containing protein kinase 2, Rho associated protein kinase 2, Rho kinase 2, ROCK 2, Rock II |
Immunogen | KLH conjugated synthetic peptide derived from human ROCK2:1001-1300/1388 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Subcellular location | Cytoplasm, Cell membrane |
Predicted MW. | 161 kDa |
Observed MW. | 161 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat, Rabbit | 1:500-1:2000 | muscle, brain , colon carcinoma |
Background
ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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