bad
- 50 μL
Product Information
Description | BAD rabbit polyclonal |
Protein full name | BCL2-associated agonist of cell death |
Synonyms | BAD, BBC2, BBC6 |
Immunogen | Recombinant protein corresponding to Mouse BAD |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 18 kDa |
Observed MW. | 18-25 kDa |
Uniprot ID | Q92934 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 3000 | Jurkat, HeLa |
Background
BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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