NOS2/inos
- 50 μL
Product Information
| Description | iNOS rabbit polyclonal |
| Protein full name | iNOS |
| Synonyms | NOS, INOS, NOS2A, HEP-NOS, iNOS, NOS2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 500-730 of human iNOS (NP_000616.3). |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 131kDa |
| Observed MW. | 130 kDa |
| Uniprot ID | P35228 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 2000 | Raw 264.7 |
Background
NOS2, also named as iNOS and NOS2A, produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission, antimicrobial and antitumoral activities. NOS2 is a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. iNOS has a very short half-life due to rapid degradation by calpain. iNOS monomer is a direct substrate of calpain I and can be cleaved by calpain I at the canonical CaM-binding site(503-532aa) of iNOS, and then a ~70kD band can be detected by western. This antibody is specific to NOS2.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|