
ATG-7
- 50 μL
Product Information
Description | ATG7 rabbit polyclonal |
Protein full name | ATG7 autophagy related 7 homolog (S. cerevisiae) |
Synonyms | APG7 LIKE, APG7L, ATG7, Autophagy related protein 7, GSA7, hAGP7 |
Immunogen | Recombinant protein corresponding to Mouse ATG7 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytosol,Nucleoplasm,Plasma membrane |
Predicted MW. | 78 kDa |
Observed MW. | 68-78 kDa |
Uniprot ID | O95352 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse,Rat, Pig,Prawns, Swine,Turtle | 1:500-1:1000 | Jurkat, THP-1 |
Background
Atg7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for Atg conjugation and autophagosome formation. Atg7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. There are several isoforms of ATG7 protein ranged from 68 kDa to 78 kDa.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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