CDK6
- 50 μL
Product Information
Description | CDK6 rabbit polyclonal |
Protein full name | CDK6 |
Synonyms | CDK6, MCPH12, PLSTIRE |
Immunogen | A synthetic peptide of human CDK6 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytoplasm, Nucleus, Cytoskeleton |
Predicted MW. | 37kDa |
Observed MW. | 37 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 2000 | liver, brain |
Background
Cyclin-dependent kinase 6 (p40cdk6 also known as PLSTIRE) belongs to a family of proteins designated as cdks. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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