WNT1
- 50 μL
Product Information
Description | WNT1 rabbit polyclonal |
Protein full name | Wingless-Type MMTV Integration Site Family, Member 1 |
Synonyms | WNT1, BMND16, INT1, OI15 |
Immunogen | Recombinant protein corresponding to Mouse WNT1 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted, Extracellular matrix, Extracellular space |
Predicted MW. | 40 kDa |
Observed MW. | 49 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 4000 | liver, heart, kidney, liver |
Background
Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal. The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade. Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor. Extensive research has shown that deregulation of these pathways or its components can lead to cancer.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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