ROCK1
- 50 μL
Product Information
Description | ROCK1 rabbit polyclonal |
Protein full name | Rho-associated, coiled-coil containing protein kinase 1 |
Synonyms | p160 ROCK 1, P160ROCK, PRO0435, ROCK1 |
Immunogen | |
Isotype | IgG |
Purity | Antigen affinity purification |
Subcellular location | Endoplasmic reticulum |
Predicted MW. | 35 kDa |
Observed MW. | 150-160 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive |
WB | Human, Mouse, Rat | 1: 500 -1: 5000 | spleen |
Background
ROCK1, also named as p160ROCK and NY-REN-35, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. ROCK1 phosphorylates and activates DAPK3, which then regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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