CD3
- 50 μL
Product Information
Description | CD3 mouse monoclonal |
Protein full name | T-cell surface glycoprotein CD3 epsilon chain |
Synonyms | T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e) |
Immunogen | Synthesized peptide derived from human CD3 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Membrane |
Uniprot ID | P07766 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human | 1: 100-1:500 | tonsil |
Background
CD3e molecule(CD3E) Homo sapiens The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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