C-caspase3
￥0
货号：YB13447
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | C-Caspase-3 rabbit polyclonal |
| Protein full name | Cleaved-Caspase-3 |
| Synonyms | CASP3, CPP32, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1 |
| Immunogen | Synthesized peptide derived from the Internal region of human Caspase-3 p17. at AA rangle: 100-180 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm. |
| Uniprot ID | P42574, P70677, P55213 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 50-1: 300 | tonsil, ulcerative colitis colon |
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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