Anti-VEGFA Rabbit pAb
- 100 μL
Product Information
Description | VEGFA rabbit polyclonal antibody |
Protein full name | Vascular endothelial growth factor A |
Synonyms | VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse VEGFA |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted |
Predicted MW. | 34-45 kDa |
Observed MW. | 34-45 kDa |
Uniprot ID | P15692, Q00731, P16612 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | B16,liver cancer,kidney |
Background
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .
Images
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Western blot analysis of VEGFA (GB11034) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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