
Anti-Bax Rabbit pAb
- 100 μL
Product Information
| Description | Bax rabbit polyclonal antibody |
| Protein full name | Apoptosis regulator Bax |
| Synonyms | BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bax |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. |
21 kDa |
| Observed MW. | 21 kDa |
| Uniprot ID | Q07812,Q07813,Q63690 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | HeLa,HepG2,colon cancer,liver cancer |
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Images
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Western blot analysis of BAX (GB11007) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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