Anti-Collagen I Rabbit pAb
- 50 μL
Product Information
| Description | Collagen I rabbit polyclonal |
| Protein full name |
Collagen alpha-1(I) chain |
|
Synonyms |
Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Collagen alpha-1(I) chain |
| Isotype | IgG |
| Purity | Affinity purification |
|
Predicted MW. |
139 kDa |
|
Observed MW. |
125 kDa |
| Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1:1000-1:2000 | XXX |
Background
Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Images
|
Western blot analysis of Collagen I (GB13022-2) at dilution of 1:1000. Lane 1: NIH3T3 cell lysate Lane 2: A431 cell lysate Lane 3: 293 cell lysate Lane 4: Mouse liver tissue lysate Lane 5: Mouse ovary tissue lysate Lane 6: Mouse lung tissue lysate Lane 7: Rat liver tissue lysate Lane 8: Rat ovary tissue lysate Lane 9: Rat lung tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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