产品信息

蛋白质全称	LRP伴侣蛋白MESD
别名	BOCA, KIAA0081, LDLR chaperone MESD, MESD, MESDC2, Mesoderm development protein
Uniprot ID	Q9ERE7
免疫原	小鼠MESDC2重组蛋白
抗体亚型	IgG
预测分子量./观测分子量.	25 kDa / 23 kDa
纯化方式	亲和纯化

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应用

应用	物种	稀释	阳性样品
WB 免疫印迹	大鼠	1: 500-1: 1000	胎盘

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背景

Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs) . Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction . Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 . May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.

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图像

WB检测MESDC2蛋白(货号 GB114504). 样品: 经RIPA裂解液(货号G2002)处理的蛋白质. 封闭: 封闭: 3%脱脂牛奶(货号GC310001)溶于TBST溶液, 室温孵育1小时. —抗: 1: 1000稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号GB23303), 1: 5000稀释, 室温孵育1小时.

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储存

储存条件	在-20℃下储存一年, 避免反复冻融.
储存缓冲液	含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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注意:

1.本产品仅供研究使用.

2.建议用一抗稀释液(G2025)稀释本产品.