Anti-Bax Rabbit pAb
- 100 μL
Product Information
Description | Bax rabbit polyclonal antibody |
Protein full name | Apoptosis regulator Bax |
Synonyms | BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bax |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Mitochondrion membrane, Cytoplasm |
Uniprot ID | Q07812,Q07813,Q63690 |
Applications
applications | species | dilution | Positive tissue |
IHC | Human,Mouse,Rat | 1:500-1:1000 | Stomach cancer, lung,colon |
| IF | Human,Mouse,Rat | 1:500-1:1000 | Stomach cancer, lung,colon |
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Images
| Immunohistochemistry of paraffin embedded human breast cancer using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse small intestine using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat pneumonia using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded human gastric cancer using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded human stomach using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded rat myocardial infarction using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded rat spleen using Bax (GB11007-1) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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