CASPASE7
- 50 μL
Product Information
| Description | Caspase 7/P20 rabbit polyclonal |
| Protein full name | caspase 7, apoptosis-related cysteine peptidase |
| Synonyms | Apoptotic protease Mch 3, CASP 7, CASP7, Caspase 7, Caspase7, CMH 1, ICE LAP3, ICE like apoptotic protease 3, MCH3 |
| Immunogen | Caspase 7/p20 fusion protein Ag25904 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 34 kDa |
| Observed MW. | 35 kDa |
| Uniprot ID | P55210 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse | 1: 500-1: 1000 | Jurkat, HEK-293, LNCaP, MCF-7, PC-3 |
Background
Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury. Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9. The protein is involved in the activation cascade of caspases responsible for apoptosis execution.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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