Bcl-2
￥0
货号：YB13450
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | Bcl-2 Mouse monoclonal |
| Protein full name | Apoptosis regulator Bcl-2 |
| Synonyms | Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2_HUMAN, C430015F12Rik, D630044D05Rik |
| Immunogen | Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Mitochondrion outer membrane, Nucleus membrane, Endoplasmic reticulum membrane |
| Uniprot ID | P10415 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 50-1:200 | breast carcinoma, salivary gland, UM xenografts |
Background
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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