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survivin

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货号:YB13188
品牌:YIKE
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  • 50 μL
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Product Information


Description Survivin  Rabbit monoclonal
Protein full name Baculoviral IAP repeat-containing protein 5
Synonyms API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, EPR 1, IAP4, SURVIVIN
Immunogen Recombinant protein corresponding to
Mouse Survivin
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus, Cytoplasm.
Uniprot ID Q15392,O70201,Q9JHY7




Applications


Applications Species Dilution Positive Tissue
IHC Human 1: 250 - 1: 500 urinary bladder carcinoma, colonic adenocarcinoma, bladder carcinoma




Background

Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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