
TRAP/CD40L
- 50 μL
Product Information
| Description | TRAP/CD40L rabbit polyclonal |
| Protein full name | TNF related activation protein |
| Synonyms | TNFSF5, CD 154, CD154, CD 40L, CD154, CD154 antigen, CD40 homologue, CD40 ligand, CD40LG, gp39, hCD40L, HIGM1, Hyper IgM syndrome, IGM, IMD3, Ly62, T B cell activating molecule |
| Immunogen | Synthetic peptide corresponding to TRAP/CD40L. surrounding amino acid 246 of human CD40 Ligand |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 29 kDa |
| Observed MW. | 65 kDa |
| Uniprot ID | P29965 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1:000 | muscle |
Background
TNF, as also known as TNF-alpha, or cachectin, is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is expressed as a 26 kDa membrane bound protein and is then cleaved by TNF-alpha converting enzyme (TACE) to release the soluble 17 kDa monomer, which forms homotrimers in circulation. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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