Anti-Phospho-AKT1 (T308) Rabbit pAb
- 50 μL
Product Information
Description | AKT1 (phospho S473) rabbit polyclonal |
Protein full name | RAC-alpha serine/threonine-protein kinase |
Synonyms | Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC |
Immunogen | A synthesized peptide derived from human AKT1 around the phosphorylation site of Thr308. |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Predicted MW. | 56 kDa |
Observed MW. | 56-60 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain |
IHC | Human, Mouse, Rat | 1: 50-1: 200 | ovary, mammary cancer, liver cancer, pancreatic cancer, gastric cancer, |
Background
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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