P-IkBa (Ser32)
¥0
货号:YB13473
规格:
- 50 μL
数量:
Product Information
| Description | phospho-IKB alpha rabbit polyclonal |
| Protein full name | phospho-IKB alpha |
| Synonyms | IKB alpha (phospho S32), IKB alpha (phospho Ser32), p-IKB alpha (phospho S32), I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse phospho-IKB alpha |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 36kDa |
| Observed MW. | 40kDa |
| Uniprot ID | P25963 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | H M R Mk | 1: 500-1: 2000 | HeLa , NIH/3T3 |
Background
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha . NFKB1 or NFKB2 is bound to REL, RELA , or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).
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