p-TAU(s396)
- 50 μL
Product Information
| Description | Tau (phospho S396) rabbit polyclonal |
| Protein full name | Tau (phospho S396) |
| Synonyms | Tau (phospho S396), p-Tau (phospho S396);Tau (phospho S396), p-Tau (phospho S396), Tau(Phospho-Ser396), MAPT, Microtuble-associted protein Tau |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human Tau aa 350 to the C-terminus |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm, Cell membrane |
| Uniprot ID | P10636, P10637 , P19332 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 10000-1: 50000 | glioblastoma, cerebrum, brain |
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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