P-MEK1/2(Ser221)
￥0
货号：YB13557
规格：
- 50 μL
数量：
Product Information
| Description | Phospho-MEK1/2 rabbit polyclonal |
| Protein full name | Phospho-MEK1/2 |
| Synonyms | Phospho-MAP2K1, Phospho-MAP2K2 |
| Immunogen | A synthesized peptide derived from human MEK1/2 around the phosphorylation site of Ser221. |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 44 kDa |
| Observed MW. | 45 kDa |
| Uniprot ID | Q02750 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB |
Human, Mouse, Rat | 1: 500-1: 2000 | Widely expressed, with extremely low levels in brain. |
Background
MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling. It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated. This antibody is specific to MEK1.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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