p-jnk (Thr183/Tyr185)
- 50 μL
Product Information
| Description | phospho-JNK1 + 2 + 3 rabbit polyclonal |
| Protein full name | phospho-JNK1 + 2 + 3 |
| Synonyms | JNK1 + JNK2 + JNK3(phospho T183+T183), JNK1 (phospho T183 + Y185), p-JNK1 (phospho T183 + Y185), MAPK8 (phospho T183/Y185), JNK1 + JNK2 + JNK3 (phospho Thr183+Tyr185), JNK1 + 2 + 3 (phospho Thr183+Tyr185), p-JNK |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mousephospho-JNK1 + 2 + 3 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 48 kDa |
| Observed MW. | 46/54 kDa |
| Uniprot ID | P45983, P45984, P53779 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | NIH/3T3, C6, 293T |
Background
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has some isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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