P-STAT3(Ser727)
- 50 μL
Product Information
| Description | phospho-STAT3rabbit polyclonal |
| Protein full name | phospho-STAT3 |
| Synonyms | STAT3 (phospho S727), p-STAT3 (phospho S727), STAT3(Phospho Ser727), STAT3(Phospho S727), p-STAT3(Ser727), Acute Phase Response Factor, APRF, DNA binding protein APRF, Signal Transductor and Activator of Transcription 3, STAT 3 |
| Immunogen | Synthesized peptide derived from human Stat3 around the phosphorylation site of S727 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 88kDa |
| Observed MW. | 86kDa |
| Uniprot ID | P40763 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human,Mouse,Rat,Monkey | 1: 1000-1: 5000 | Heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas |
Background
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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