P-ERK
- 50 μL
Product Information
| Description | P-ERK rabbit polyclonal |
| Protein full name | Phospho-ERK1/2 (Tyr204) Antibody |
| Synonyms | ERK1, ERK2, ERT1, ERT2 |
| Immunogen | A synthesized peptide derived from human ERK1/2 around the phosphorylation site of Tyr204. |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nucleus |
| Uniprot ID | P27361, P28482 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 50-1: 200 | breast carcinoma |
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.
Images
Storage
| Storage | Stable for 12 months from date of receipt. |
| Storage Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
