P-AKT(S473)
￥0
货号：YB13470
规格：
- 50 μL
数量：
Product Information
| Description | Phospho-AKT1 rabbit polyclonal |
| Protein full name | Phospho-Akt1 |
| Synonyms | MGC9965, MGC99656, Oncogene AKT1, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein Kinase B Alpha, Protein kinase B, Proto-oncogene c-Akt, RAC Alpha, RAC alpha serine/threonine protein kinase, RAC, RAC PK Alpha, Rac protein kinase alpha |
| Immunogen | A synthesized peptide derived from human AKT1 around the phosphorylation site of Thr308 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 56 kDa |
| Observed MW. | 55-60 kDa |
| Uniprot ID | P31749, P31750, P47196 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | prostate cancer |
Background
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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