Anti-Phospho-pan-AKT1/2/3 (S473) Rabbit pAb
- 50 μL
Product Information
Description | P-AKT rabbit polyclonal |
Protein full name | Phospho-pan-AKT1/2/3 (Ser473) Antibody |
Synonyms | AKT1, AKT2, AKT3, PKB, RAC, STK2 |
Immunogen | A synthesized peptide derived from human Akt around the phosphorylation site of Ser473. |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytoplasm, Nucleus, Cell membrane |
Uniprot ID | P31749, P31751, Q9Y243 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 50-1: 200 | lung |
Background
AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis (PubMed:15526160, PubMed:11882383, PubMed:21620960, PubMed:21432781). This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates (PubMed:15526160, PubMed:11882383, PubMed:21620960, PubMed:21432781).
Images
Storage
| Storage | Store at -20 °C.Stable for 12 months from date of receipt. |
| Storage Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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