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p-s6 rp

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货号:YB13582
规格:
  • 50 μL
数量:

Product Information


Description Phospho-S6 Ribosomal Protein (Ser235/236)rabbit polyclonal
Protein full name 40S ribosomal protein S6
Synonyms Threonine Kinase 1, Threonine-Protein Kinase
Immunogen Recombinant protein corresponding to
Mouse Phospho-S6 Ribosomal Protein (Ser235/236)
Isotype IgG
Purity Affinity purification
Subcellular location Cell membrane, Cytoskeleton, Nucleus
Uniprot ID P62753




Applications


Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1: 1000-1: 2000 NIH/3T3




Background

Ribosomal protein S6 (RPS6),Phosphoprotein NP33.It may play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphorylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.It's molecular weight is about 29kd.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).


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