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P-JAK1(TYR 1022)

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货号:YB13588
规格:
  • 50 μL
数量:

Product Information


Description P-JAK1(TYR 1022)  rabbit polyclonal
Protein full name P-JAK1(TYR 1022)
Synonyms JAK 1, JAK 1A, JAK 1B, JAK-1, JAK1, JAK1_HUMAN, JAK1A, JAK1B, Janus kinase 1 (a protein tyrosine kinase), Janus kinase 1, JTK3, Tyrosine protein kinase JAK 1, Tyrosine protein kinase JAK1, Tyrosine-protein kinase JAK1.
Immunogen KLH conjugated Synthesised phosphopeptide derived from human Jak1 around the phosphorylation site of Tyr1034 + Tyr1035:KE(p-Y)(p-Y)TV
Isotype IgG
Purity Affinity purification
Predicted MW. 133 kDa
Observed MW. 133 kDa
Uniprot ID P23458




Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 2000 spleen




Background

Janus kinase 1(JAK1), is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 is essential for signaling for certain type I and type II cytokines. JAK1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).


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