p-IRS-1
￥0
货号：YB13542
规格：
- 50 μL
数量：
Product Information
| Description | p-IRS-1 rabbit polyclonal |
| Protein full name | Insulin receptor substrate 1 |
| Synonyms | IRS1, HIRS-1, insulin receptor substrate 1 |
| Immunogen | A synthetic phosphorylated peptide around S307 of human IRS1 (NP_005535.1). |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 131 kDa |
| Observed MW. | 200 kDa |
| Uniprot ID | P35568 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | brian |
Background
Insulin receptor substrate 1 (IRS1) was the first cloned and characterized member of the IRS family which are involved in insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) signaling. IRS1 is phosphorylated by insulin receptor tyrosine kinase and is involved in various cellular processes including DNA repair fidelity, transcriptional activity, and cell growth can support tumor development and progression. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance .
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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