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P-EIF2α

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货号:YB13547
规格:
  • 50 μL
数量:

Product Information


Description p-eIF2αrabbit polyclonal
Protein full name Phospho-eIF2 alpha(Ser51)/HRP
Synonyms EIF2S1 (phospho S51), EIF2S1 (phospho-Ser51), CDA 02, CDA02, eIF 2 alpha, EIF 2, EIF 2A, EIF-2alpha, EIF2, EIF2A, EIF2alpha, eIF2S1, Eukaryotic Translation Initiation Factor 2 alpha
Immunogen KLH conjugated synthesised phosphopeptide derived from human eIF2 alpha around the phosphorylation site of Ser51 [EL(p-S)RR]
Isotype IgG
Purity Affinity purification
Predicted MW. 36 kDa
Observed MW. 36 kDa
Uniprot ID Q9BY44




Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat
Cow
1: 50-1: 200 stomach, placenta, skeletal muscle




Background

EIF2S1 is one subunit of the translation initiation factor EIF2, which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the YTP bound to eIF-2 and release of an eIF-2-GDP binary complex.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).


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