P-P53(Ser392)
- 50 μL
Product Information
| Description | Phospho-p53 rabbit polyclonal |
| Protein full name | phospho-P53 |
| Synonyms | p-P53 (Ser6), p-P53 (S6), Widespread p53, Wtp53, Antigen NY-CO-13, Cellular tumor antigen p53, Cys 51 Stop, HGNC11998, LFS1, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, Phosphoprotein p53, TP53 |
| Immunogen | Recombinant protein corresponding to Mouse Phospho-p53 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 44 kDa |
| Observed MW. | 53 kDa |
| Uniprot ID | P04637 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human,Mouse,Rat | 1: 1000 | spleen, colon |
Background
TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. TP53 Localizes in the nucleus in most cells but found in the cytoplasm in some cells.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).
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