Anti-PI 3 Kinase catalytic subunit alpha/PIK3CA Rabbit pAb
- 50 μL
Product Information
Description | PI 3 Kinase catalytic subunit alpha/PIK3CA rabbit polyclonal |
Protein full name | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
Synonyms | PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha, p110alpha, PtdIns-3-kinase subunit p110-alpha, PIK3CA |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 401-600 of human PIK3CA (NP_006209.2). |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cell membrane, Cytoplasm |
Predicted MW. | 124 kDa |
Observed MW. | 115 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 2000 | HeLa |
IHC | Human, Mouse, Rat | 1: 50-1: 100 | kidney , colon carcinoma, |
IF | Human, Mouse | 1: 50-1: 100 | HeLa, NIH/3T3 |
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
