SMAD7
¥0
货号:YB13553
规格:
- 50 μL
数量:
Product Information
| Description | Smad7 rabbit polyclonal |
| Protein full name | SMAD family member 7 |
| Synonyms | CRCS3, hSMAD7, MAD homolog 7, MAD homolog 8, MADH7, MADH8, Mothers against DPP homolog 7, Mothers against DPP homolog 8, SMAD 7, SMAD family member 7, SMAD7 |
| Immunogen | SMAD7 fusion protein Ag13688 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 46 kDa |
| Observed MW. | 46 kDa |
| Uniprot ID | O15105 |
Applications
| Applications | Species | Dilution | Positive |
| WB | Human, Rat | 1: 500-1: 2000 | liver, lung, skeletal muscle, kidney |
Background
SMAD7, also named as Mothers against decapentaplegic homolog 7, is a 426 amino acid protein, which belongs to the dwarfin/SMAD family. SMAD7 Interaction with NEDD4L or RNF111 induces translocation from the nucleus to the cytoplasm. SMAD7 as antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).
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