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SMAD7

¥0
货号:YB13553
规格:
  • 50 μL
数量:

Product Information


Description Smad7 rabbit polyclonal
Protein full name SMAD family member 7
Synonyms CRCS3, hSMAD7, MAD homolog 7, MAD homolog 8, MADH7, MADH8, Mothers against DPP homolog 7, Mothers against DPP homolog 8, SMAD 7, SMAD family member 7, SMAD7
Immunogen SMAD7 fusion protein Ag13688
Isotype IgG
Purity Affinity purification
Predicted MW. 46 kDa
Observed MW. 46 kDa
Uniprot ID O15105




Applications


Applications Species Dilution Positive
WB Human, Rat 1: 500-1: 2000 liver, lung, skeletal muscle, kidney




Background

SMAD7, also named as Mothers against decapentaplegic homolog 7, is a 426 amino acid protein, which belongs to the dwarfin/SMAD family. SMAD7 Interaction with NEDD4L or RNF111 induces translocation from the nucleus to the cytoplasm. SMAD7 as antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).


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