H3
- 50 μL
Product Information
| Description | H3 Mouse polyclonal |
| Protein full name | Histone H3.1/Histone H3.2/Histone H3.3 |
| Synonyms | HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/ |
| Immunogen | Recombinant protein corresponding to Mouse H3 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 15 kDa |
| Observed MW. | 15 kDa |
| Uniprot ID | Q9Y5N1 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat, Yeast | 1: 2000-1: 5000 | brain, skeletal muscle, liver |
Background
Histone-H3, histone cluster 2, H3a is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone-H3 is expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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