Anti-MUM1 Mouse mAb
- 100 μL
Product Information
Protein full name | Interferon regulatory factor 4 |
Synonyms | EXPAND1, HSPC211, MUM 1, MUM1, Protein expandere |
Immunogen | Recombinant protein corresponding to Human MUM1 |
Uniprot ID | Q15306 |
Isotype | IgG2a,k |
Purity | Affinity purification |
Subcellular location | Nucleus |
Predicted MW. / Observed MW. | 50 kDa / 50 kDa |
Applications
IHC/IF | Human, Mouse, Rat | 1: 300-1: 900 | colon, spleen |
Background
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
Images
| IHC analysis of MUM1(YB12172). Sample: Human tonsil, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Human colon, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Human esophageal carcinoma, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Mouse colon, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Mouse spleen, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Rat colon, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
| IHC analysis of MUM1(YB12172). Sample: Rat spleen, 4% PFA (Y1112) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (Y1212), pressure cooker 2min. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (YB23312), 1: 200, RT, 1h. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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