P27
￥0
货号：YB13554
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | P27rabbit polyclonal |
| Protein full name | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| Synonyms | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27, P27, KIP1, P27KIP1 |
| Immunogen | P27, KIP1 fusion protein Ag22582 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 22 kDa |
| Observed MW. | 27 kDa |
| Uniprot ID | P46527 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB |
Human, Mouse, Cow, Rat, Sheep | 1: 1000-1: 4000 | HepG2, HeLa, NIH/3T3, Jurkat |
Background
CDKN1B, also named as P27 or KIP1, is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. P27 binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controlling cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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