CDKN2A/P16
￥0
货号：YB13524
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | CDKN2A / p16INK4a rabbit polyclonal |
| Protein full name | CDKN2A / p16INK4a |
| Synonyms | CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 20 to the C-terminus of human CDKN2A / p16INK4a |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 17kDa |
| Observed MW. | 17 kDa |
| Uniprot ID | P42771 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | 293T, PC-3, HeLa, MCF7 |
Background
CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins proteins were reported. Two of them named p16-INK4 and p14 are sharing 50% identity. The third one -p14(ARF) is entirely unrelated. 10883-1-AP reacts with p16 specifically. P16 plays an essential role in regulating the cell cycle, and mutations in p16 increase the risk of developing various cancers, including melanoma.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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