Anti-Cyclin D1 Rabbit pAb
- 100 μL
Product Information
Description | Cyclin D1 rabbit polyclonal antibody |
Protein full name | G1/S-specific cyclin-D1 |
Synonyms | CCND1, BCL1, D11S287E, PRAD1, U21B31, cyclin D1 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 33 kDa |
Uniprot ID | P25322 |
Applications
applications | species | dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, kidney, brain |
Background
The protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDKs (Cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.
Images
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Western blot analysis of Cyclin D1 (YB11090) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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